Phenytoin ideal body weight
WebJun 2, 2024 · The total phenytoin reference range varies by age, as follows: Children and adults: 10-20 µg/mL [ 4] Neonates: 8-15 µg/mL. Toxic phenytoin levels are defined as … WebDec 28, 2024 · To determine the ideal body weight for a female, you can use the Devine formula. In kilograms: 45.5 kg + 2.3 kg for every inch over 5 feet. In pounds: 100.3 lb + 5.1 lb for every inch over 5 feet. For example, for a 5 ft 4-inch female, the ideal weight is 55 kg (121.25 lb). Remember, this is only an estimation.
Phenytoin ideal body weight
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WebMar 21, 2024 · Initial dose: 5 mg/kg/day orally in 2 or 3 equally divided doses, with subsequent dosage individualized to a maximum of 300 mg orally daily. Maintenance … WebNational Center for Biotechnology Information
WebPatients: Twelve healthy volunteers within 15% of ideal body weight and with no clinically significant abnormalities on physical examination, medical history, or laboratory assessment. Interventions: Volunteers randomly received a 30-minute infusion of phenytoin sodium 250 mg (250 mg/5 ml) or an equimolar dose of fosphenytoin 375 mg (375 mg/5 ml). WebSep 1, 2024 · The established target therapeutic range for phenytoin is generally accepted as 10–20 mcg/mL of total phenytoin or 1–2 mcg/mL of free phenytoin; targeting concentrations at the higher end of this range for patients in status epilepticus may be appropriate, however there is little evidence to support this practice [1], [7], [8].
WebSep 6, 2024 · 1 to 9 years: 0.8 mg/kg ideal body weight/hour 9 to 12 years: 0.7 mg/kg ideal body weight/hour 12 to 16 years, cigarette or marijuana smoker: 0.7 mg/kg ideal body weight/hour 12 to 16 years, nonsmoker: 0.5 mg/kg ideal body weight/hour 16 years and older, otherwise healthy nonsmoker: 0.4 mg/kg ideal body weight/hour WebWe assess the safety and efficacy of fosphenytoin loading doses in patients with different body mass indices (BMIs). Methods: A retrospective chart review was conducted in 410 …
WebFeb 17, 2024 · Weight-based dosing (off-label): Note: May be used to individualize loading dose and estimate initial maintenance dose requirements according to body weight. …
Web-Calculate ideal body weight (IBW) as follows (height in cm, and weight in kg): Men: IBW (kg)=50+0.91x (height in cm -152) Women: IBW (kg)=45+0.91x (height in cm -152) ... Initiate phenytoin therapy or any other alternative anti-convulsant prophylactic therapy (e.g., benzodiazepines, valproic acid or levetiracetam) prior to BUSULFEX treatment red acura rdxWebOct 17, 1977 · Note: program uses adjusted body weight for all calculations. Loading Dose (IV): 10 – 20 mg/kg . Recommended infusion rate for adults: 40-50 mg/min. Elderly (>65): Recommended infusion rate: 20-25 mg/min. … kline family dentistrykline dishwasherWebPhenytoin disposition in obesity. Determination of loading dose. Fourteen obese subjects (mean body weight, 124 kg; percent of ideal body weight [IBW], 178%) and ten control … red activity ring on apple watchWebSince phenytoin is a relatively lipid-soluble drug, obese patients have a larger volume of distribution (in liters) equal to: L V 0.65 [(IBW) 1.33(ABW IBW)] (obese in L) = + − kg where ABW is actual body weight in kg and IBW is ideal body weight in kg. Table 1.11-2. Reported Values of V max and K m Age K m (Mean ± SD) V max (Mean ± SD)a ... kline chiropractorWebResults: The median dose of fosphenytoin administered was 19 mg/kg (interquartile range 15–20). The most frequently encountered adverse event was hypotension, which … kline family foundationWebOct 3, 2024 · ideal body weight = 45.4 + 0.89 x (170 – 152.4) + 4.5 = 65 kg Obviously, large variations exist for mg/kg dosing depending on which metric is used. Enoxaparin A … red adair co. inc