Heparg differentiation
WebHepaRG® Differentiation Medium Supplement. Product category: Culture medium. Product code: ADD721C. For the use of HepaRG® cell line, as supplement for differentiation … WebIn the present study, we evaluated the effect of alcohol on hepatocyte differentiation in relationship with changes of iron metabolism in HepaRG cells. This unique bipotent human cell line can differentiate into hepatocytes and biliary epithelial cells, paralleling liver development. Results showed that alcohol reduced cell viability, total ...
Heparg differentiation
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WebThe cytochromes P450 (CYPs) represent a large gene superfamily that plays an important role in the metabolism of both exogenous and endogenous compounds. We have reported that the testis-specific Y-encoded-like proteins (TSPYLs) are novel CYP gene Web9 apr. 2014 · Differentiation of HepaRG Progenitors Into Cholangiocytes HepaRG-HB were treated for 2 days with IL-6 (10 ng/ml), then for 2 days with sodium taurocholate hydrate (10 nM) and then for 2 days with sodium taurocholate hydrate (10 nM) and sodium butyrate (1.8 μM) to prevent spontaneous differentiation along the hepatocytic lineage.
Web一站式科研服务平台. 学术工具. 文档翻译; 收录引证; 论文查重; 文档转换 Web9 apr. 2014 · Differentiation of HepaRG Progenitors Into Cholangiocytes HepaRG-HB were treated for 2 days with IL-6 (10 ng/ml), then for 2 days with sodium taurocholate hydrate …
WebThe HepaRG cell line, which is a human bipotent progenitor cell line capable to differentiate toward two different cell phenotypes (i.e., biliary-like and hepatocyte … WebFully differentiated HepaRG™ cells are the hepatic cell line of choice for in vitro study in toxicology and drug trials. They are derived from a hepatoblast-like progenitor (HepaRG …
Web25 jan. 2024 · The HepaRG cell line is a human bipotent progenitor cell line that can be differentiated into HLCs and biliary epithelial cells [ 19 ]. Whole-genome expression profiling showed that HepaRG cells are remarkably similar to human hepatocyte populations [ 52 ].
WebGibco ™ HepaRG cells have the unique properties of maintaining significant levels of hepatic cell functions, of being CYP450 inducible and supporting the complete replicative … inbc addressWebOur results indicated that the enhancement of hepatic functions in 3D-cultured HepaRG cells was induced by selective hepatocyte differentiation and accelerated hepatocyte … inbc backgammonWeb1 aug. 2024 · In contrast to many hepatoma cell lines, differentiated HepaRG cells exhibit specific liver functions resembling those of adult primary human hepatocytes, including abundant CYP450 enzymes, such as CYP1A2, CYP2B6, CYP2E1, and CYP3A4, phase II enzymes, drug transporters, and ligand-activated nuclear receptors [3], [4], [5], [6], [7]. inbcunowWeb12 feb. 2024 · HepaRG is a bipotent stem cell line that can be differentiated towards hepatocyte-like and biliary-like cells. The entire cultivation process requires 1 month and relies on the addition of 2% dimethyl sulfoxide (DMSO) to the culture. inchydoney hotel phone numberWebHepaRG™ cells exhibit many characteristics of primary human hepatocytes and are essentially a single donor. These features allow users to obtain physiological relevant results for metabolism-based drug-drug interactions without the concern of donor variability and limited lot sizes that come with relying on donor tissue. inbc groupWeb1 jan. 2010 · The HepaRG cell line, which is a human bipotent progenitor cell line capable to differentiate toward two different cell phenotypes (i.e., biliary-like and hepatocyte-like cells), has been established from a liver tumor associated with chronic hepatitis C. inchydoney house for saleWeb14 okt. 2024 · Differentiated HepaRG (dHepaRG) are considered the best surrogate model to primary human hepatocytes (PHH) and are susceptible to several hepatotropic … inbc service plan