WebJan 1, 2016 · The PDIM fraction was eluted at 30.5–34.5 min, and family of phthiocerol dimycocerosate eluted earlier than that of phthiodiolone dimycocerosate (see supplementary Fig. 1B). PDIM fractions from several injections were collected and pooled, dried under a stream of nitrogen, and subjected to further structural analyses as … WebThe current review will focus on phthiocerol dimycocerosates (PDIMs), a long-known and well-studied group of complex lipids found in the M. tuberculosis cell envelope. …
Characterization of phthiocerol and phthiodiolone dimycocerosate …
WebAmong the few characterized genes that have products involved in the pathogenicity of Mycobacterium tuberculosis, the etiological agent of tuberculosis, are those of the … WebJul 23, 2024 · The virulence lipid phthiocerol dimycocerosate (PDIM) is an outer membrane virulence lipid in both M. marinum and M. tuberculosis. PDIM-deficient … maniglie designer famosi
Phthiocerol Dimycocerosates of M. tuberculosis Participate in ...
WebFeb 1, 2024 · Follow-up experiments confirmed this prediction. Transfer of a representative mutant pptT allele into wild-type Mtb conferred resistance to 8918, regulated depletion of PptT hypersensitized Mtb to 8918 without affecting susceptibility to TB drugs with unrelated mechanisms of action, and exposure of Mtb to 8918 inhibited the production of mycolic … WebJan 4, 2024 · Phthiocerol dimycocerosates (PDIM), glycolipids found on the outer surface of virulent members of the Mycobacterium tuberculosis … WebJan 1, 2016 · The PDIM fraction was eluted at 30.5–34.5 min, and family of phthiocerol dimycocerosate eluted earlier than that of phthiodiolone dimycocerosate (see … maniglie giesse ricambi